Rosenberg, VanCamp, Trosko and Mansour: platinum compounds as antitumour agents

What changed

Reported selected platinum compounds' antitumour activity in mouse models.

Scientific scope

The record is the exact four-author 1969 Nature paper. Its evidence is preclinical and does not establish human efficacy, dosing, safety or the performance of every platinum drug; the 1965 bacterial cell-division observation is a distinct contribution.

Evidence

The linked sources identify this contribution and its scope. WRS has not independently reconstructed the scientific claims. The record is the exact four-author 1969 Nature paper. Its evidence is preclinical and does not establish human efficacy, dosing, safety or the performance of every platinum drug; the 1965 bacterial cell-division observation is a distinct contribution.

Contributors

• Barnett Rosenberg · SCIENCE: Named source author of the scoped work; individual effort shares are not measured.
• Loretta VanCamp · SCIENCE: Named source author of the scoped work; individual effort shares are not measured.
• James E. Trosko · SCIENCE: Named source author of the scoped work; individual effort shares are not measured.
• Virginia H. Mansour · SCIENCE: Named source author of the scoped work; individual effort shares are not measured.

• Nature page for platinum antitumour paper
• CiNii record for platinum antitumour paper

Provisional WRS assessment, edition 2026-10-16.1. Independent expert calibration is pending. This grade does not certify correctness or assign ownership.

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