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Rosenberg, VanCamp, Trosko and Mansour: platinum compounds as antitumour agents

Reported preliminary antitumour activity of selected platinum compounds in mouse tumour models, establishing a preclinical bridge from platinum-induced bacterial growth effects to cancer chemotherapy research.

What is recorded here?

Reported preliminary antitumour activity of selected platinum compounds in mouse tumour models, establishing a preclinical bridge from platinum-induced bacterial growth effects to cancer chemotherapy research.

Source-linked catalogue note. A detailed explanatory guide has not yet been prepared for this entry.

Scientific scope

The record is the exact four-author 1969 Nature paper. Its evidence is preclinical and does not establish human efficacy, dosing, safety or the performance of every platinum drug; the 1965 bacterial cell-division observation is a distinct contribution.

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People and systems

Barnett Rosenberg; Loretta VanCamp; James E. Trosko; Virginia H. Mansour

The named authors contributed to this scoped work; individual effort shares and later applications are not assigned by the byline.

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Documented countries / regions: United States

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English catalogue narrative

Rosenberg, VanCamp, Trosko and Mansour: platinum compounds as antitumour agents

Reported preliminary antitumour activity of selected platinum compounds in mouse tumour models, establishing a preclinical bridge from platinum-induced bacterial growth effects to cancer chemotherapy research.

Scientific scope

The record is the exact four-author 1969 Nature paper. Its evidence is preclinical and does not establish human efficacy, dosing, safety or the performance of every platinum drug; the 1965 bacterial cell-division observation is a distinct contribution.

Reading status

This is a source-linked WRS catalogue note. A full explanatory guide and independent scientific reconstruction have not been completed for this entry. Read the identified original work for its complete narrative and arguments.

People and systems

Barnett Rosenberg; Loretta VanCamp; James E. Trosko; Virginia H. Mansour

The named authors contributed to this scoped work; individual effort shares and later applications are not assigned by the byline.

Original sources