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Nirenberg & Matthaei: reading an RNA instruction

Contribution grade

Molecular biology · Scoped scientific or research-capability contribution

Reference score100,000Provisional editorial estimate of this exact contribution; its grade is assessed separately.

What changed

Used synthetic poly-U RNA in a cell-free system to direct phenylalanine incorporation, providing a decisive entry point into deciphering the genetic code.

Scientific scope

Used synthetic poly-U RNA in a cell-free system to direct phenylalanine incorporation, providing a decisive entry point into deciphering the genetic code. Scope limitation: This experiment concerns an initial coding assignment. Completion of the genetic code and later translation mechanisms involved additional researchers and experiments.

Evidence

Assessment uses the catalogue-linked source evidence for the stated contribution. This experiment concerns an initial coding assignment. Completion of the genetic code and later translation mechanisms involved additional researchers and experiments.

Contributors

Provisional WRS assessment, edition 2026-10-16.1. Independent expert calibration is pending. This grade does not certify correctness or assign ownership.

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