What changed
Used synthetic poly-U RNA in a cell-free system to direct phenylalanine incorporation, providing a decisive entry point into deciphering the genetic code.
Scientific scope
Used synthetic poly-U RNA in a cell-free system to direct phenylalanine incorporation, providing a decisive entry point into deciphering the genetic code. Scope limitation: This experiment concerns an initial coding assignment. Completion of the genetic code and later translation mechanisms involved additional researchers and experiments.
Evidence
Assessment uses the catalogue-linked source evidence for the stated contribution. This experiment concerns an initial coding assignment. Completion of the genetic code and later translation mechanisms involved additional researchers and experiments.
Contributors
- Marshall W. Nirenberg · SCIENCE: Named source contributor; exact labor shares are not measured.
- J. Heinrich Matthaei · SCIENCE: Named source contributor; exact labor shares are not measured.
- The dependence of cell-free protein synthesis in E. coli upon naturally occurring or synthetic polyribonucleotides
- Publisher-deposited byline: The dependence of cell-free protein synthesis in E. coli upon naturally occurring or synthetic polyribonucleotides
Provisional WRS assessment, edition 2026-10-16.1. Independent expert calibration is pending. This grade does not certify correctness or assign ownership.
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