What is recorded here?
Used synthetic poly-U RNA in a cell-free system to direct phenylalanine incorporation, providing a decisive entry point into deciphering the genetic code.
Source-linked catalogue note. A detailed explanatory guide has not yet been prepared for this entry.
Scientific scope
This experiment concerns an initial coding assignment. Completion of the genetic code and later translation mechanisms involved additional researchers and experiments.
Read the original work
- The dependence of cell-free protein synthesis in E. coli upon naturally occurring or synthetic polyribonucleotides
- Publisher-deposited byline: The dependence of cell-free protein synthesis in E. coli upon naturally occurring or synthetic polyribonucleotides
This English explanation is an editorial reading view. It does not replace the complete original work or certify its science.
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People and systems
Marshall W. Nirenberg; J. Heinrich Matthaei
Full byline of the specified publication; original laboratory roles remain in the source.
Research locations and affiliations
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Documented countries / regions: United States
National Institutes of Health, Bethesda, Maryland.
English catalogue narrative
Nirenberg & Matthaei: reading an RNA instruction
Used synthetic poly-U RNA in a cell-free system to direct phenylalanine incorporation, providing a decisive entry point into deciphering the genetic code.
Scientific scope
This experiment concerns an initial coding assignment. Completion of the genetic code and later translation mechanisms involved additional researchers and experiments.
Reading status
This is a source-linked WRS catalogue note. A full explanatory guide and independent scientific reconstruction have not been completed for this entry. Read the identified original work for its complete narrative and arguments.
People and systems
Marshall W. Nirenberg; J. Heinrich Matthaei
Full byline of the specified publication; original laboratory roles remain in the source.
Original sources
- [The dependence of cell-free protein synthesis in
E. coli upon naturally occurring or synthetic polyribonucleotides](https://pmc.ncbi.nlm.nih.gov/articles/PMC223178/)
- [Publisher-deposited byline: The dependence of cell-free protein synthesis in
E. coli upon naturally occurring or synthetic polyribonucleotides](https://api.crossref.org/works/10.1073%2Fpnas.47.10.1588)