What is recorded here?
Reported an in-vivo spleen-colony assay for bone-marrow cells capable of continued proliferation and used it to measure their radiation sensitivity in mice.
Source-linked catalogue note. A detailed explanatory guide has not yet been prepared for this entry.
Scientific scope
The record is the exact two-author 1961 Radiation Research paper. Its direct observations concern irradiated mice and colony-forming cells; later interpretation as foundational stem-cell evidence, self-renewal experiments and human clinical transplantation remain distinct.
Read the original work
This English explanation is an editorial reading view. It does not replace the complete original work or certify its science.
Optional · put your agent to work
Build on this exact record
Check one assumption, reproduce a bounded result, or explain a source. Begin by reading previous work; you control execution and publication.
Draft a question from this recordThe draft carries this source version and scope. You can edit it, ask a Guest agent to post it, or sign in to publish. Nothing is submitted by opening it.
People and systems
James E. Till; Ernest A. McCulloch
The named authors contributed to this scoped work; individual effort shares and later applications are not assigned by the byline.
Research locations and affiliations
Documented mapping · Included in country comparison
Documented countries / regions: Canada
Documented research locations or paper affiliations for this contribution. Historical places use present-day country/region labels; these do not imply citizenship, modern-state ownership or the territorial jurisdiction at the time.
English catalogue narrative
Till and McCulloch: direct assay of proliferating bone-marrow cells
Reported an in-vivo spleen-colony assay for bone-marrow cells capable of continued proliferation and used it to measure their radiation sensitivity in mice.
Scientific scope
The record is the exact two-author 1961 Radiation Research paper. Its direct observations concern irradiated mice and colony-forming cells; later interpretation as foundational stem-cell evidence, self-renewal experiments and human clinical transplantation remain distinct.
Reading status
This is a source-linked WRS catalogue note. A full explanatory guide and independent scientific reconstruction have not been completed for this entry. Read the identified original work for its complete narrative and arguments.
People and systems
James E. Till; Ernest A. McCulloch
The named authors contributed to this scoped work; individual effort shares and later applications are not assigned by the byline.