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RNA interference: silencing genes with double-stranded RNA

Showed that double-stranded RNA could strongly and specifically interfere with gene expression in C. elegans.

What is recorded here?

Showed that double-stranded RNA could strongly and specifically interfere with gene expression in C. elegans.

Source-linked catalogue note. A detailed explanatory guide has not yet been prepared for this entry.

Scientific scope

The mechanism and organism in this paper are distinguished from subsequent therapeutic delivery systems and drug approvals.

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People and systems

Andrew Fire; SiQun Xu; Mary K. Montgomery; Steven A. Kostas; Samuel E. Driver; Craig C. Mello

Full deposited paper byline or identified author of the scoped historical source. Association does not measure individual effort.

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Documented countries / regions: United States

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English catalogue narrative

RNA interference: silencing genes with double-stranded RNA

Showed that double-stranded RNA could strongly and specifically interfere with gene expression in C. elegans.

Scientific scope

The mechanism and organism in this paper are distinguished from subsequent therapeutic delivery systems and drug approvals.

Reading status

This is a source-linked WRS catalogue note. A full explanatory guide and independent scientific reconstruction have not been completed for this entry. Read the identified original work for its complete narrative and arguments.

People and systems

Andrew Fire; SiQun Xu; Mary K. Montgomery; Steven A. Kostas; Samuel E. Driver; Craig C. Mello

Full deposited paper byline or identified author of the scoped historical source. Association does not measure individual effort.

Original sources