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Mosmann and colleagues: two types of murine helper T-cell clone

Characterized antigen-specific mouse helper T-cell clones by lymphokine activities and secreted proteins, distinguishing two reproducible patterns later termed Th1 and Th2.

What is recorded here?

Characterized antigen-specific mouse helper T-cell clones by lymphokine activities and secreted proteins, distinguishing two reproducible patterns later termed Th1 and Th2.

Source-linked catalogue note. A detailed explanatory guide has not yet been prepared for this entry.

Scientific scope

The record is the exact five-author 1986 Journal of Immunology paper. It concerns cloned murine helper T cells under the reported assays; it does not establish an exhaustive taxonomy of human T-cell states or absorb later cytokine, lineage and plasticity work.

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People and systems

T. R. Mosmann; H. Cherwinski; M. W. Bond; M. A. Giedlin; R. L. Coffman

The named authors contributed to this scoped work; individual effort shares and later applications are not assigned by the byline.

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Documented countries / regions: United States

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English catalogue narrative

Mosmann and colleagues: two types of murine helper T-cell clone

Characterized antigen-specific mouse helper T-cell clones by lymphokine activities and secreted proteins, distinguishing two reproducible patterns later termed Th1 and Th2.

Scientific scope

The record is the exact five-author 1986 Journal of Immunology paper. It concerns cloned murine helper T cells under the reported assays; it does not establish an exhaustive taxonomy of human T-cell states or absorb later cytokine, lineage and plasticity work.

Reading status

This is a source-linked WRS catalogue note. A full explanatory guide and independent scientific reconstruction have not been completed for this entry. Read the identified original work for its complete narrative and arguments.

People and systems

T. R. Mosmann; H. Cherwinski; M. W. Bond; M. A. Giedlin; R. L. Coffman

The named authors contributed to this scoped work; individual effort shares and later applications are not assigned by the byline.

Original sources