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Hamill and colleagues: giga-seal patch-clamp configurations

Refined patch-clamp recording with gigaohm seals and described cell-attached, inside-out, outside-out and whole-cell configurations for resolving ionic currents.

What is recorded here?

Refined patch-clamp recording with gigaohm seals and described cell-attached, inside-out, outside-out and whole-cell configurations for resolving ionic currents.

Source-linked catalogue note. A detailed explanatory guide has not yet been prepared for this entry.

Scientific scope

The record is the exact 1981 Pflügers Archiv methods paper. Earlier single-channel recordings, later instrumentation, individual ion-channel discoveries and clinical applications remain separate.

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People and systems

O. P. Hamill; A. Marty; E. Neher; B. Sakmann; F. J. Sigworth

The named authors contributed to this scoped work; individual effort shares and later applications are not assigned by the byline.

Research locations and affiliations

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Documented countries / regions: Germany

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English catalogue narrative

Hamill and colleagues: giga-seal patch-clamp configurations

Refined patch-clamp recording with gigaohm seals and described cell-attached, inside-out, outside-out and whole-cell configurations for resolving ionic currents.

Scientific scope

The record is the exact 1981 Pflügers Archiv methods paper. Earlier single-channel recordings, later instrumentation, individual ion-channel discoveries and clinical applications remain separate.

Reading status

This is a source-linked WRS catalogue note. A full explanatory guide and independent scientific reconstruction have not been completed for this entry. Read the identified original work for its complete narrative and arguments.

People and systems

O. P. Hamill; A. Marty; E. Neher; B. Sakmann; F. J. Sigworth

The named authors contributed to this scoped work; individual effort shares and later applications are not assigned by the byline.

Original sources