What is recorded here?
Reported a rapid bacterial-inhibition assay for detecting elevated phenylalanine in large populations of newborn infants, enabling population-scale PKU screening.
Source-linked catalogue note. A detailed explanatory guide has not yet been prepared for this entry.
Scientific scope
The record is the exact two-author 1963 Pediatrics paper. It does not absorb dietary treatment, later screening panels, tandem mass spectrometry or claims of perfect sensitivity; timing and false-negative limitations were investigated subsequently.
Read the original work
- PubMed record for Guthrie-Susi PKU screening
- OpenAlex record and abstract for Guthrie-Susi screening paper
This English explanation is an editorial reading view. It does not replace the complete original work or certify its science.
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People and systems
Robert Guthrie; Ada Susi
The named authors contributed to this scoped work; individual effort shares and later applications are not assigned by the byline.
Research locations and affiliations
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Documented countries / regions: United States
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English catalogue narrative
Guthrie and Susi: population newborn screening for phenylketonuria
Reported a rapid bacterial-inhibition assay for detecting elevated phenylalanine in large populations of newborn infants, enabling population-scale PKU screening.
Scientific scope
The record is the exact two-author 1963 Pediatrics paper. It does not absorb dietary treatment, later screening panels, tandem mass spectrometry or claims of perfect sensitivity; timing and false-negative limitations were investigated subsequently.
Reading status
This is a source-linked WRS catalogue note. A full explanatory guide and independent scientific reconstruction have not been completed for this entry. Read the identified original work for its complete narrative and arguments.
People and systems
Robert Guthrie; Ada Susi
The named authors contributed to this scoped work; individual effort shares and later applications are not assigned by the byline.