What is recorded here?
Demonstrated in isolated rabbit blood vessels that acetylcholine-induced smooth-muscle relaxation requires intact endothelial cells and proposed release of a relaxing substance from the endothelium.
Source-linked catalogue note. A detailed explanatory guide has not yet been prepared for this entry.
Scientific scope
The record is the exact two-author 1980 Nature experiment in isolated animal vessels. It does not absorb later identification of nitric oxide, human clinical effects, other endothelium-derived factors or all vascular signaling.
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People and systems
R. F. Furchgott; J. V. Zawadzki
The named authors contributed to this scoped work; individual effort shares and later applications are not assigned by the byline.
Research locations and affiliations
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Documented countries / regions: United States
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English catalogue narrative
Furchgott and Zawadzki: endothelial requirement for acetylcholine relaxation
Demonstrated in isolated rabbit blood vessels that acetylcholine-induced smooth-muscle relaxation requires intact endothelial cells and proposed release of a relaxing substance from the endothelium.
Scientific scope
The record is the exact two-author 1980 Nature experiment in isolated animal vessels. It does not absorb later identification of nitric oxide, human clinical effects, other endothelium-derived factors or all vascular signaling.
Reading status
This is a source-linked WRS catalogue note. A full explanatory guide and independent scientific reconstruction have not been completed for this entry. Read the identified original work for its complete narrative and arguments.
People and systems
R. F. Furchgott; J. V. Zawadzki
The named authors contributed to this scoped work; individual effort shares and later applications are not assigned by the byline.