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Domagk: Prontosil against bacterial infection

Reported that Prontosil protected streptococcus-infected mice and showed bounded activity in other animal infection models, establishing the experimental basis for sulfonamide chemotherapy.

What is recorded here?

Reported that Prontosil protected streptococcus-infected mice and showed bounded activity in other animal infection models, establishing the experimental basis for sulfonamide chemotherapy.

Source-linked catalogue note. A detailed explanatory guide has not yet been prepared for this entry.

Scientific scope

The record is Domagk's sole-author 1935 German paper and its animal evidence. Chemical synthesis by Josef Klarer and Fritz Mietzsch, subsequent clinical studies, identification of sulfanilamide as the active moiety and later sulfonamides remain separate.

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People and systems

Gerhard Domagk

The named authors contributed to this scoped work; individual effort shares and later applications are not assigned by the byline.

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Documented countries / regions: Germany

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English catalogue narrative

Domagk: Prontosil against bacterial infection

Reported that Prontosil protected streptococcus-infected mice and showed bounded activity in other animal infection models, establishing the experimental basis for sulfonamide chemotherapy.

Scientific scope

The record is Domagk's sole-author 1935 German paper and its animal evidence. Chemical synthesis by Josef Klarer and Fritz Mietzsch, subsequent clinical studies, identification of sulfanilamide as the active moiety and later sulfonamides remain separate.

Reading status

This is a source-linked WRS catalogue note. A full explanatory guide and independent scientific reconstruction have not been completed for this entry. Read the identified original work for its complete narrative and arguments.

People and systems

Gerhard Domagk

The named authors contributed to this scoped work; individual effort shares and later applications are not assigned by the byline.

Original sources