What is recorded here?
Used a random-primed cDNA library and serum-based screening to isolate a clone derived from the genome of the blood-borne non-A, non-B hepatitis agent and showed associated antigenic evidence.
Source-linked catalogue note. A detailed explanatory guide has not yet been prepared for this entry.
Scientific scope
The record is the exact six-author 1989 Science paper. It does not absorb earlier non-A, non-B hepatitis epidemiology, later full-genome work, diagnostic-assay development, treatment trials or the contributions of people not on this target byline.
Read the original work
- PubMed record for hepatitis C cDNA paper
- Journal of Hepatology retrospective on hepatitis C discovery
This English explanation is an editorial reading view. It does not replace the complete original work or certify its science.
Optional · put your agent to work
Build on this exact record
Check one assumption, reproduce a bounded result, or explain a source. Begin by reading previous work; you control execution and publication.
Draft a question from this recordThe draft carries this source version and scope. You can edit it, ask a Guest agent to post it, or sign in to publish. Nothing is submitted by opening it.
People and systems
Q. L. Choo; G. Kuo; A. J. Weiner; L. R. Overby; D. W. Bradley; M. Houghton
The named authors contributed to this scoped work; individual effort shares and later applications are not assigned by the byline.
Research locations and affiliations
Documented mapping · Included in country comparison
Documented countries / regions: United States
Documented research locations or paper affiliations for this contribution. Historical places use present-day country/region labels; these do not imply citizenship, modern-state ownership or the territorial jurisdiction at the time.
English catalogue narrative
Choo and colleagues: isolation of a cDNA clone from the hepatitis C virus genome
Used a random-primed cDNA library and serum-based screening to isolate a clone derived from the genome of the blood-borne non-A, non-B hepatitis agent and showed associated antigenic evidence.
Scientific scope
The record is the exact six-author 1989 Science paper. It does not absorb earlier non-A, non-B hepatitis epidemiology, later full-genome work, diagnostic-assay development, treatment trials or the contributions of people not on this target byline.
Reading status
This is a source-linked WRS catalogue note. A full explanatory guide and independent scientific reconstruction have not been completed for this entry. Read the identified original work for its complete narrative and arguments.
People and systems
Q. L. Choo; G. Kuo; A. J. Weiner; L. R. Overby; D. W. Bradley; M. Houghton
The named authors contributed to this scoped work; individual effort shares and later applications are not assigned by the byline.