What is recorded here?
Reported early clinical use of cyclosporin A in seven cadaveric renal-allograft recipients, documenting immunosuppressive promise together with serious nephrotoxicity, hepatotoxicity and adverse outcomes.
Source-linked catalogue note. A detailed explanatory guide has not yet been prepared for this entry.
Scientific scope
The record is the exact nine-author 1978 clinical report in seven recipients. It does not establish modern transplant-regimen efficacy or safety, absorb earlier animal studies or generalize its outcomes to other organs and protocols.
Read the original work
- PubMed record for cyclosporin renal-allograft report
- Full-text historical account of early cyclosporin use
This English explanation is an editorial reading view. It does not replace the complete original work or certify its science.
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People and systems
R. Y. Calne; D. J. White; S. Thiru; D. B. Evans; P. McMaster; D. C. Dunn; G. N. Craddock; B. D. Pentlow; K. Rolles
The named authors contributed to this scoped work; individual effort shares and later applications are not assigned by the byline.
Research locations and affiliations
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Documented countries / regions: United Kingdom
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English catalogue narrative
Calne and colleagues: cyclosporin A in renal allograft recipients
Reported early clinical use of cyclosporin A in seven cadaveric renal-allograft recipients, documenting immunosuppressive promise together with serious nephrotoxicity, hepatotoxicity and adverse outcomes.
Scientific scope
The record is the exact nine-author 1978 clinical report in seven recipients. It does not establish modern transplant-regimen efficacy or safety, absorb earlier animal studies or generalize its outcomes to other organs and protocols.
Reading status
This is a source-linked WRS catalogue note. A full explanatory guide and independent scientific reconstruction have not been completed for this entry. Read the identified original work for its complete narrative and arguments.
People and systems
R. Y. Calne; D. J. White; S. Thiru; D. B. Evans; P. McMaster; D. C. Dunn; G. N. Craddock; B. D. Pentlow; K. Rolles
The named authors contributed to this scoped work; individual effort shares and later applications are not assigned by the byline.