The DNA structure proposal and modern protein prediction solve different scientific tasks. Their connection is a growing ability to reason about molecular structure, built by generations of scientists.
AlphaFold 2 made a major advance in the protein-prediction setting described in its paper. AlphaFold 3 extends structure modeling to biomolecular interactions. Human authors, experimental data and system development remain part of both records.
A predicted structure carries a different kind of evidence from a measured structure. Read the stated evaluation and limitations before using a prediction as experimental confirmation.
Read the research records
- The DNA double helix: model and diffraction evidence
- AlphaFold 2: protein structure prediction
- AlphaFold 3: structures of biomolecular interactions
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Compare the prediction, its confidence and the experimental evidence for one specific target.
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