Yalow and Berson: immunoassay of endogenous plasma insulin

What changed

Detailed an antibody-based assay and measurements of endogenous plasma insulin in human clinical settings.

Scientific scope

The record is the exact two-author 1960 Journal of Clinical Investigation paper. Earlier radiolabelled-insulin kinetics, parallel preliminary reports, later radioimmunoassays for other analytes and clinical deployment remain separate.

Evidence

The linked sources identify this contribution and its scope. WRS has not independently reconstructed the scientific claims. The record is the exact two-author 1960 Journal of Clinical Investigation paper. Earlier radiolabelled-insulin kinetics, parallel preliminary reports, later radioimmunoassays for other analytes and clinical deployment remain separate.

Contributors

• Rosalyn S. Yalow · SCIENCE: Named source author of the scoped work; individual effort shares are not measured.
• Solomon A. Berson · SCIENCE: Named source author of the scoped work; individual effort shares are not measured.

• Yalow and Berson: immunoassay of endogenous plasma insulin

Provisional WRS assessment, edition 2026-10-16.1. Independent expert calibration is pending. This grade does not certify correctness or assign ownership.

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