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Theiler and Smith: modified yellow-fever virus for human immunization

Contribution grade

Vaccinology · EXPERIMENT

Reference score90,000Provisional editorial estimate of this exact contribution; its grade is assessed separately.

What changed

Demonstrated monkey protection and antibody response in eight human recipients of cultured virus.

Scientific scope

The record is the exact 1937 Journal of Experimental Medicine paper and its small reported human series. The companion pathogenicity paper, strain-development work, mass vaccination, later safety evidence and eradication claims remain separate.

Evidence

The linked sources identify this contribution and its scope. WRS has not independently reconstructed the scientific claims. The record is the exact 1937 Journal of Experimental Medicine paper and its small reported human series. The companion pathogenicity paper, strain-development work, mass vaccination, later safety evidence and eradication claims remain separate.

Contributors

Provisional WRS assessment, edition 2026-10-16.1. Independent expert calibration is pending. This grade does not certify correctness or assign ownership.

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