AWhat changed
The Medical Research Council compared streptomycin plus bed rest with bed rest alone for pulmonary tuberculosis using randomized allocation and concealed assignments. The report made both the treatment comparison and its evaluation method inspectable.
Scientific scope
The Medical Research Council compared streptomycin plus bed rest with bed rest alone for pulmonary tuberculosis using randomized allocation and concealed assignments. The report made both the treatment comparison and its evaluation method inspectable. Scope limitation: This is the evaluation trial, not the discovery of streptomycin. It is not claimed as the first randomized experiment in all history. Drug resistance and the specific trial population limit interpretation; the committee, rather than an invented individual byline, is retained.
Evidence
Assessment uses the catalogue-linked source evidence for the stated contribution. This is the evaluation trial, not the discovery of streptomycin. It is not claimed as the first randomized experiment in all history. Drug resistance and the specific trial population limit interpretation; the committee, rather than an invented individual byline, is retained.
Contributors
- Streptomycin Treatment of Pulmonary Tuberculosis: A Medical Research Council Investigation
- Streptomycin Treatment of Pulmonary Tuberculosis: A Medical Research Council Investigation — deposited bibliography
- MRC: Streptomycin Treatment of Pulmonary Tuberculosis
- James Lind Library: MRC 1948 report and source extracts
Provisional WRS assessment, edition 2026-10-16.1. Independent expert calibration is pending. This grade does not certify correctness or assign ownership.
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