Doll and Hill: investigating the link between smoking and lung cancer

What changed

Doll and Hill compared smoking histories in patients with lung carcinoma and controls. Their case-control study became an important early contribution to the accumulating evidence on tobacco and lung cancer.

Scientific scope

Doll and Hill compared smoking histories in patients with lung carcinoma and controls. Their case-control study became an important early contribution to the accumulating evidence on tobacco and lung cancer. Scope limitation: This observational study was not a randomized exposure experiment and did not alone establish every causal claim or modern risk estimate. Later prospective studies and independent investigations supplied distinct evidence.

Evidence

Assessment uses the catalogue-linked source evidence for the stated contribution. This observational study was not a randomized exposure experiment and did not alone establish every causal claim or modern risk estimate. Later prospective studies and independent investigations supplied distinct evidence.

Contributors

• Richard Doll · SCIENCE: Named source contributor; exact labor shares are not measured.
• A. Bradford Hill · SCIENCE: Named source contributor; exact labor shares are not measured.

• Smoking and Carcinoma of the Lung
• Smoking and Carcinoma of the Lung — deposited bibliography
• Doll and Hill: Smoking and Carcinoma of the Lung

Provisional WRS assessment, edition 2026-10-16.1. Independent expert calibration is pending. This grade does not certify correctness or assign ownership.

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