AWhat changed
Lander and Botstein developed methods for locating factors underlying quantitative traits using genetic linkage maps, including interval mapping and selective genotyping. The framework helped connect measured traits to regions of a genome.
Scientific scope
Lander and Botstein developed methods for locating factors underlying quantitative traits using genetic linkage maps, including interval mapping and selective genotyping. The framework helped connect measured traits to regions of a genome. Scope limitation: A mapped region is not automatically a causal gene, a useful breeding target in every population or a released crop variety. Earlier linkage theory and experimental mapping supplied important foundations.
Evidence
Assessment uses the catalogue-linked source evidence for the stated contribution. A mapped region is not automatically a causal gene, a useful breeding target in every population or a released crop variety. Earlier linkage theory and experimental mapping supplied important foundations.
Contributors
- E S Lander · SCIENCE: Named source contributor; exact labor shares are not measured.
- D Botstein · SCIENCE: Named source contributor; exact labor shares are not measured.
- Mapping mendelian factors underlying quantitative traits using RFLP linkage maps.
- Mapping mendelian factors underlying quantitative traits using RFLP linkage maps. — deposited bibliography
- Lander and Botstein: original abstract and bibliography
Provisional WRS assessment, edition 2026-10-16.1. Independent expert calibration is pending. This grade does not certify correctness or assign ownership.
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