Ogawa and colleagues: BOLD-sensitive functional brain mapping with MRI

What changed

Task-related human cortical activity could be mapped with intrinsic MRI contrast.

Scientific scope

Seven-author 1992 PNAS paper; earlier BOLD finding, other human fMRI papers and connectivity analyses separate.

Evidence

The linked sources identify this contribution and its scope. WRS has not independently reconstructed the scientific claims. The record is the exact 1992 PNAS paper. Earlier BOLD contrast observations, contemporaneous human fMRI papers, structural MRI and later functional-connectivity methods remain separate.

Contributors

• Seiji Ogawa · SCIENCE: Named source author of the scoped work; individual effort shares are not measured.
• David W. Tank · SCIENCE: Named source author of the scoped work; individual effort shares are not measured.
• Ravi S. Menon · SCIENCE: Named source author of the scoped work; individual effort shares are not measured.
• Jutta M. Ellermann · SCIENCE: Named source author of the scoped work; individual effort shares are not measured.
• Seong-Gi Kim · SCIENCE: Named source author of the scoped work; individual effort shares are not measured.
• Hellmut Merkle · SCIENCE: Named source author of the scoped work; individual effort shares are not measured.
• Kamil Ugurbil · SCIENCE: Named source author of the scoped work; individual effort shares are not measured.

• PubMed record for Ogawa et al. functional MRI paper
• Crossref record for Ogawa fMRI paper

Provisional WRS assessment, edition 2026-10-16.1. Independent expert calibration is pending. This grade does not certify correctness or assign ownership.

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