AWhat changed
Fused immune cells and myeloma cells to create cell lines producing antibodies with a defined specificity.
Scientific scope
Fused immune cells and myeloma cells to create cell lines producing antibodies with a defined specificity. Scope limitation: The original mouse hybridoma method differs from later humanization, clinical approvals and antibody manufacturing systems.
Evidence
Assessment uses the catalogue-linked source evidence for the stated contribution. The original mouse hybridoma method differs from later humanization, clinical approvals and antibody manufacturing systems.
Contributors
- G. KÖHLER · SCIENCE: Named source contributor; exact labor shares are not measured.
- C. MILSTEIN · SCIENCE: Named source contributor; exact labor shares are not measured.
- Continuous cultures of fused cells secreting antibody of predefined specificity
- Continuous cultures of fused cells secreting antibody of predefined specificity — deposited bibliography
Provisional WRS assessment, edition 2026-10-16.1. Independent expert calibration is pending. This grade does not certify correctness or assign ownership.
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