Mantel and Haenszel: statistical analysis of retrospective disease studies

What changed

Developed stratified procedures for testing association and estimating a common relative risk from retrospective disease-study data while controlling categorical confounding factors.

Scientific scope

The record is the exact 1959 Journal of the National Cancer Institute paper. Cochran’s related work, later conditional logistic regression, generalized CMH procedures and software implementations remain separate.

Evidence

The linked sources identify this contribution and its scope. WRS has not independently reconstructed the scientific claims. The record is the exact 1959 Journal of the National Cancer Institute paper. Cochran’s related work, later conditional logistic regression, generalized CMH procedures and software implementations remain separate.

Contributors

• Nathan Mantel · SCIENCE: Named source author of the scoped work; individual effort shares are not measured.
• William Haenszel · SCIENCE: Named source author of the scoped work; individual effort shares are not measured.

• Oxford Academic record for Mantel–Haenszel retrospective-study methods
• PubMed record for Mantel–Haenszel 1959

Provisional WRS assessment, edition 2026-10-16.1. Independent expert calibration is pending. This grade does not certify correctness or assign ownership.

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