Liggins and Howie: controlled trial of antepartum glucocorticoid treatment

What changed

Tested antepartum betamethasone in 282 mothers and reported neonatal respiratory outcomes.

Scientific scope

The record is the exact two-author 1972 Pediatrics trial report. It does not erase the authors' call for further trials, absorb later meta-analyses and guidelines or claim universal benefit across all gestations and regimens.

Evidence

The linked sources identify this contribution and its scope. WRS has not independently reconstructed the scientific claims. The record is the exact two-author 1972 Pediatrics trial report. It does not erase the authors' call for further trials, absorb later meta-analyses and guidelines or claim universal benefit across all gestations and regimens.

Contributors

• Graham C. Liggins · SCIENCE: Named source author of the scoped work; individual effort shares are not measured.
• Ross N. Howie · SCIENCE: Named source author of the scoped work; individual effort shares are not measured.

• Pediatrics record for antepartum glucocorticoid trial

Provisional WRS assessment, edition 2026-10-16.1. Independent expert calibration is pending. This grade does not certify correctness or assign ownership.

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