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Knaus and colleagues: APACHE II severity classification

Contribution grade

Surgery, anaesthesia and critical care · EMPIRICAL

Reference score145,000Provisional editorial estimate of this exact contribution; its grade is assessed separately.

What changed

Developed and assessed an ICU severity score from acute physiology, age and chronic health status.

Scientific scope

The record is the exact four-author 1985 development-and-validation study. The score stratifies risk in the reported settings; it is not an individual prognosis guarantee and requires recalibration across populations and eras.

Evidence

The linked sources identify this contribution and its scope. WRS has not independently reconstructed the scientific claims. The record is the exact four-author 1985 development-and-validation study. The score stratifies risk in the reported settings; it is not an individual prognosis guarantee and requires recalibration across populations and eras.

Contributors

Provisional WRS assessment, edition 2026-10-16.1. Independent expert calibration is pending. This grade does not certify correctness or assign ownership.

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