AWhat changed
Used defined factors to turn mouse fibroblasts into cells with pluripotent stem-cell properties.
Scientific scope
Used defined factors to turn mouse fibroblasts into cells with pluripotent stem-cell properties. Scope limitation: The 2006 mouse result precedes human iPS cells. Reprogramming does not by itself establish a safe or effective clinical therapy.
Evidence
Assessment uses the catalogue-linked source evidence for the stated contribution. The 2006 mouse result precedes human iPS cells. Reprogramming does not by itself establish a safe or effective clinical therapy.
Contributors
- Kazutoshi Takahashi · SCIENCE: Named source contributor; exact labor shares are not measured.
- Shinya Yamanaka · SCIENCE: Named source contributor; exact labor shares are not measured.
- Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
- Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors — deposited bibliography
Provisional WRS assessment, edition 2026-10-16.1. Independent expert calibration is pending. This grade does not certify correctness or assign ownership.
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