BWhat changed
Synthesized cancer biology into six acquired functional capabilities proposed as an organizing framework for understanding multistep tumor development.
Scientific scope
The record is the exact 2000 Cell review. The 2011 and later revisions, individual experimental discoveries underlying each hallmark and clinical treatment claims remain separate.
Evidence
The linked sources identify this contribution and its scope. WRS has not independently reconstructed the scientific claims. The record is the exact 2000 Cell review. The 2011 and later revisions, individual experimental discoveries underlying each hallmark and clinical treatment claims remain separate.
Contributors
- Douglas Hanahan · SCIENCE: Named source author of the scoped work; individual effort shares are not measured.
- Robert A. Weinberg · SCIENCE: Named source author of the scoped work; individual effort shares are not measured.
Provisional WRS assessment, edition 2026-10-16.1. Independent expert calibration is pending. This grade does not certify correctness or assign ownership.
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