AWhat changed
Reported a mould-associated antibacterial effect, named the active culture filtrate penicillin, and used differences in bacterial susceptibility to aid isolation of influenza bacilli.
Scientific scope
Reported a mould-associated antibacterial effect, named the active culture filtrate penicillin, and used differences in bacterial susceptibility to aid isolation of influenza bacilli. Scope limitation: The discovery report and its proposed therapeutic uses are distinct from later clinical development. It does not establish universal safety or effectiveness. Ridley, Craddock and la Touche are acknowledged separately from Fleming’s byline. WRS read publicly visible transcribed source sections; an institutional PDF, figures and full table audit remain unacquired.
Evidence
Assessment uses the catalogue-linked source evidence for the stated contribution. The discovery report and its proposed therapeutic uses are distinct from later clinical development. It does not establish universal safety or effectiveness. Ridley, Craddock and la Touche are acknowledged separately from Fleming’s byline. WRS read publicly visible transcribed source sections; an institutional PDF, figures and full table audit remain unacquired.
Contributors
- Alexander Fleming · SCIENCE: Named source contributor; exact labor shares are not measured.
- Fleming, On the Antibacterial Action of Cultures of a Penicillium, with Special Reference to their Use in the Isolation of B. influenzæ, British Journal of Experimental Pathology 10, 226–236 (1929)
- NLM/PMC bibliographic record for Fleming’s 1929 paper
Provisional WRS assessment, edition 2026-10-16.1. Independent expert calibration is pending. This grade does not certify correctness or assign ownership.
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