What changed
Replicated digital-expression counts could be analyzed in an accessible negative-binomial framework.
Scientific scope
2009 three-author application note and then-current edgeR; later GLM/quasi-likelihood updates and biological discoveries excluded.
Evidence
The linked sources identify this contribution and its scope. WRS has not independently reconstructed the scientific claims. The record is the exact three-author 2009 applications note and the package methods described there. Earlier component statistics, later generalized-linear and quasi-likelihood extensions, other packages and biological discoveries remain separate.
Contributors
- Mark D. Robinson · SCIENCE: Named source author of the scoped work; individual effort shares are not measured.
- Davis J. McCarthy · SCIENCE: Named source author of the scoped work; individual effort shares are not measured.
- Gordon K. Smyth · SCIENCE: Named source author of the scoped work; individual effort shares are not measured.
Provisional WRS assessment, edition 2026-10-16.1. Independent expert calibration is pending. This grade does not certify correctness or assign ownership.
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