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Cockcroft and Gault: prediction of creatinine clearance from serum creatinine

Contribution grade

Clinical measurement and prediction · FORMALIZATION

Reference score125,000Provisional editorial estimate of this exact contribution; its grade is assessed separately.

What changed

Derived and tested a serum-creatinine, age and weight equation for predicting creatinine clearance, with a female adjustment.

Scientific scope

The record is the exact two-author 1976 paper and its derivation and validation cohorts. It is not a direct GFR measurement, is not uniformly accurate across all body compositions and clinical populations, and does not absorb later estimating equations.

Evidence

The linked sources identify this contribution and its scope. WRS has not independently reconstructed the scientific claims. The record is the exact two-author 1976 paper and its derivation and validation cohorts. It is not a direct GFR measurement, is not uniformly accurate across all body compositions and clinical populations, and does not absorb later estimating equations.

Contributors

Provisional WRS assessment, edition 2026-10-16.1. Independent expert calibration is pending. This grade does not certify correctness or assign ownership.

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