What changed
Derived and tested a serum-creatinine, age and weight equation for predicting creatinine clearance, with a female adjustment.
Scientific scope
The record is the exact two-author 1976 paper and its derivation and validation cohorts. It is not a direct GFR measurement, is not uniformly accurate across all body compositions and clinical populations, and does not absorb later estimating equations.
Evidence
The linked sources identify this contribution and its scope. WRS has not independently reconstructed the scientific claims. The record is the exact two-author 1976 paper and its derivation and validation cohorts. It is not a direct GFR measurement, is not uniformly accurate across all body compositions and clinical populations, and does not absorb later estimating equations.
Contributors
- Donald W. Cockcroft · SCIENCE: Named source author of the scoped work; individual effort shares are not measured.
- M. Henry Gault · SCIENCE: Named source author of the scoped work; individual effort shares are not measured.
Provisional WRS assessment, edition 2026-10-16.1. Independent expert calibration is pending. This grade does not certify correctness or assign ownership.
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