Chang: fertilization of rabbit ova in vitro

What changed

Reported a repeatable procedure for fertilizing rabbit ova in vitro and evidence for normal in-vivo development after transfer of the fertilized ova.

Scientific scope

The record is the exact 1959 Nature note. Earlier capacitation work, cytological fertilization reports, later animal IVF protocols and the 1978 human IVF live birth remain separate.

Evidence

The linked sources identify this contribution and its scope. WRS has not independently reconstructed the scientific claims. The record is the exact 1959 Nature note. Earlier capacitation work, cytological fertilization reports, later animal IVF protocols and the 1978 human IVF live birth remain separate.

Contributors

• M. C. Chang · SCIENCE: Named source author of the scoped work; individual effort shares are not measured.

• Chang, Fertilization of Rabbit Ova in vitro
• Crossref record for rabbit ova fertilization

Provisional WRS assessment, edition 2026-10-16.1. Independent expert calibration is pending. This grade does not certify correctness or assign ownership.

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