Barker and Osmond: infant mortality and adult ischaemic heart disease

What changed

Reported an ecological association across England and Wales regions and cohorts.

Scientific scope

The record is the exact two-author 1986 Lancet ecological study. It does not establish individual-level causation, absorb the whole developmental-origins programme or exclude later-life confounding and alternative mechanisms.

Evidence

The linked sources identify this contribution and its scope. WRS has not independently reconstructed the scientific claims. The record is the exact two-author 1986 Lancet ecological study. It does not establish individual-level causation, absorb the whole developmental-origins programme or exclude later-life confounding and alternative mechanisms.

Contributors

• David J. P. Barker · SCIENCE: Named source author of the scoped work; individual effort shares are not measured.
• Clive Osmond · SCIENCE: Named source author of the scoped work; individual effort shares are not measured.

• PubMed record for Barker-Osmond study

Provisional WRS assessment, edition 2026-10-16.1. Independent expert calibration is pending. This grade does not certify correctness or assign ownership.

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