Apoptosis: a distinct morphology of controlled cell deletion

What changed

Controlled cell deletion became a recognizable general biological process rather than disconnected pathological observations.

Scientific scope

The 1972 morphology and proposed role; later molecular mechanisms, therapies and every earlier cell-death observation are excluded.

Evidence

The linked sources identify this contribution and its scope. WRS has not independently reconstructed the scientific claims. The source supports morphology and the proposed biological role. It does not establish later molecular pathways, clinical efficacy or ownership of every earlier observation of cell death.

Contributors

• John F. R. Kerr · SCIENCE: Named source author of the scoped work; individual effort shares are not measured.
• Andrew H. Wyllie · SCIENCE: Named source author of the scoped work; individual effort shares are not measured.
• Alastair R. Currie · SCIENCE: Named source author of the scoped work; individual effort shares are not measured.

• Kerr, Wyllie and Currie, Apoptosis (1972)

Provisional WRS assessment, edition 2026-10-16.1. Independent expert calibration is pending. This grade does not certify correctness or assign ownership.

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