Altschul et al.: the BLAST local sequence-search method

What changed

Biological sequence similarity could be searched rapidly across expanding databases.

Scientific scope

The 1990 five-author paper; later BLAST variants, service engineering and database curation are separate.

Evidence

The linked sources identify this contribution and its scope. WRS has not independently reconstructed the scientific claims. This is the original 1990 five-author BLAST paper; later variants, software engineering and database services are separate.

Contributors

• Stephen F. Altschul · SCIENCE: Named source author of the scoped work; individual effort shares are not measured.
• Warren Gish · SCIENCE: Named source author of the scoped work; individual effort shares are not measured.
• Webb Miller · SCIENCE: Named source author of the scoped work; individual effort shares are not measured.
• Eugene W. Myers · SCIENCE: Named source author of the scoped work; individual effort shares are not measured.
• David J. Lipman · SCIENCE: Named source author of the scoped work; individual effort shares are not measured.

• Altschul et al., Basic local alignment search tool (1990)

Provisional WRS assessment, edition 2026-10-16.1. Independent expert calibration is pending. This grade does not certify correctness or assign ownership.

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