BWhat changed
Predicted pathogenicity-related effects of missense variants and published a large set of predictions for human amino-acid substitutions.
Scientific scope
Predicted pathogenicity-related effects of missense variants and published a large set of predictions for human amino-acid substitutions. Scope limitation: Model classifications are predictions, not diagnoses or experimental validation of every variant. Clinical use requires additional evidence.
Evidence
Assessment uses the catalogue-linked source evidence for the stated contribution. Model classifications are predictions, not diagnoses or experimental validation of every variant. Clinical use requires additional evidence.
Contributors
- The research collaboration listed in the linked record and source byline · SCIENCE: Collective scoped contribution. The complete recorded byline remains in the research record; this label does not collapse people into one individual.
- The systems documented in the research record · EXECUTION: Source-reported system assistance within this scope; no provider attestation or independent agency is inferred.
- Accurate proteome-wide missense variant effect prediction with AlphaMissense
- Accurate proteome-wide missense variant effect prediction with AlphaMissense — deposited bibliography
Provisional WRS assessment, edition 2026-10-16.1. Independent expert calibration is pending. This grade does not certify correctness or assign ownership.
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