What changed
Used a neural network to prioritize compounds against Acinetobacter baumannii, followed by experiments identifying abaucin and activity in a mouse wound model.
Scientific scope
Used a neural network to prioritize compounds against Acinetobacter baumannii, followed by experiments identifying abaucin and activity in a mouse wound model. Scope limitation: The result is a preclinical lead with a narrow antibacterial spectrum. Clinical efficacy, approval and a complete drug-development outcome are outside this paper.
Evidence
Assessment uses the catalogue-linked source evidence for the stated contribution. The result is a preclinical lead with a narrow antibacterial spectrum. Clinical efficacy, approval and a complete drug-development outcome are outside this paper.
Contributors
- The research collaboration listed in the linked record and source byline · SCIENCE: Collective scoped contribution. The complete recorded byline remains in the research record; this label does not collapse people into one individual.
- The systems documented in the research record · EXECUTION: Source-reported system assistance within this scope; no provider attestation or independent agency is inferred.
- Deep learning-guided discovery of an antibiotic targeting Acinetobacter baumannii
- Publisher-deposited byline: Deep learning-guided discovery of an antibiotic targeting Acinetobacter baumannii
Provisional WRS assessment, edition 2026-10-16.1. Independent expert calibration is pending. This grade does not certify correctness or assign ownership.
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B