What is recorded here?
Read DNA sequences using nucleotide analogues that terminate DNA-polymerase extension at specific bases, with a bacteriophage sequence demonstration.
Source-linked catalogue note. A detailed explanatory guide has not yet been prepared for this entry.
Scientific scope
This record covers the chain-termination method. It does not claim invention of every sequencing method or include later automation, throughput advances and complete genome assemblies.
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People and systems
Frederick Sanger; S. Nicklen; Alan R. Coulson
Listed source contributors; individual labor shares are not measured
Research locations and affiliations
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Documented countries / regions: United Kingdom
All three authors: Medical Research Council Laboratory of Molecular Biology, Cambridge, England; original paper front matter.
English catalogue narrative
Sanger, Nicklen and Coulson: chain-termination DNA sequencing
Read DNA sequences using nucleotide analogues that terminate DNA-polymerase extension at specific bases, with a bacteriophage sequence demonstration.
Scientific scope
This record covers the chain-termination method. It does not claim invention of every sequencing method or include later automation, throughput advances and complete genome assemblies.
Reading status
This is a source-linked WRS catalogue note. A full explanatory guide and independent scientific reconstruction have not been completed for this entry. Read the identified original work for its complete narrative and arguments.
People and systems
Frederick Sanger; S. Nicklen; Alan R. Coulson
Listed source contributors; individual labor shares are not measured