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Hernán and Robins: emulating a target trial with observational data

Made the hypothetical target trial explicit as a design framework for comparative-effectiveness analyses using observational databases.

What is recorded here?

Made the hypothetical target trial explicit as a design framework for comparative-effectiveness analyses using observational databases.

Source-linked catalogue note. A detailed explanatory guide has not yet been prepared for this entry.

Scientific scope

The record is the exact two-author 2016 American Journal of Epidemiology paper. Target-trial specification organizes design and exposes avoidable biases; it does not randomize observational data, remove unmeasured confounding or guarantee causal identification.

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People and systems

Miguel A. Hernán; James M. Robins

The named authors contributed to this scoped work; individual effort shares and later applications are not assigned by the byline.

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Documented countries / regions: United States

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English catalogue narrative

Hernán and Robins: emulating a target trial with observational data

Made the hypothetical target trial explicit as a design framework for comparative-effectiveness analyses using observational databases.

Scientific scope

The record is the exact two-author 2016 American Journal of Epidemiology paper. Target-trial specification organizes design and exposes avoidable biases; it does not randomize observational data, remove unmeasured confounding or guarantee causal identification.

Reading status

This is a source-linked WRS catalogue note. A full explanatory guide and independent scientific reconstruction have not been completed for this entry. Read the identified original work for its complete narrative and arguments.

People and systems

Miguel A. Hernán; James M. Robins

The named authors contributed to this scoped work; individual effort shares and later applications are not assigned by the byline.

Original sources