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Greider and Blackburn: telomere terminal-transferase activity

Identified an activity in Tetrahymena cell-free extracts that added tandem telomeric repeats to suitable primers and proposed its role in chromosome-end replication.

What is recorded here?

Identified an activity in Tetrahymena cell-free extracts that added tandem telomeric repeats to suitable primers and proposed its role in chromosome-end replication.

Source-linked catalogue note. A detailed explanatory guide has not yet been prepared for this entry.

Scientific scope

The record is the exact two-author 1985 Cell paper. It reports biochemical activity in Tetrahymena extracts, not a human therapy or a complete account of telomerase composition, regulation, disease roles or later telomere biology.

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People and systems

Carol W. Greider; Elizabeth H. Blackburn

The named authors contributed to this scoped work; individual effort shares and later applications are not assigned by the byline.

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Documented countries / regions: United States

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English catalogue narrative

Greider and Blackburn: telomere terminal-transferase activity

Identified an activity in Tetrahymena cell-free extracts that added tandem telomeric repeats to suitable primers and proposed its role in chromosome-end replication.

Scientific scope

The record is the exact two-author 1985 Cell paper. It reports biochemical activity in Tetrahymena extracts, not a human therapy or a complete account of telomerase composition, regulation, disease roles or later telomere biology.

Reading status

This is a source-linked WRS catalogue note. A full explanatory guide and independent scientific reconstruction have not been completed for this entry. Read the identified original work for its complete narrative and arguments.

People and systems

Carol W. Greider; Elizabeth H. Blackburn

The named authors contributed to this scoped work; individual effort shares and later applications are not assigned by the byline.

Original sources