What is recorded here?
Proposed a simple noniterative random-effects procedure for combining treatment-effect evidence across related clinical trials while representing between-study heterogeneity.
Source-linked catalogue note. A detailed explanatory guide has not yet been prepared for this entry.
Scientific scope
The record is the exact two-author 1986 Controlled Clinical Trials paper. It is a statistical method, not clinical evidence for any treatment, and does not guarantee validity under arbitrary heterogeneity, bias or small-study conditions.
Read the original work
- PubMed record for Meta-analysis in Clinical Trials
- Authors' retrospective on DerSimonian-Laird method
This English explanation is an editorial reading view. It does not replace the complete original work or certify its science.
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People and systems
Rebecca DerSimonian; Nan Laird
The named authors contributed to this scoped work; individual effort shares and later applications are not assigned by the byline.
Research locations and affiliations
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Documented countries / regions: United States
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English catalogue narrative
DerSimonian and Laird: meta-analysis in clinical trials
Proposed a simple noniterative random-effects procedure for combining treatment-effect evidence across related clinical trials while representing between-study heterogeneity.
Scientific scope
The record is the exact two-author 1986 Controlled Clinical Trials paper. It is a statistical method, not clinical evidence for any treatment, and does not guarantee validity under arbitrary heterogeneity, bias or small-study conditions.
Reading status
This is a source-linked WRS catalogue note. A full explanatory guide and independent scientific reconstruction have not been completed for this entry. Read the identified original work for its complete narrative and arguments.
People and systems
Rebecca DerSimonian; Nan Laird
The named authors contributed to this scoped work; individual effort shares and later applications are not assigned by the byline.