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    "boundary": "The discovery report and its proposed therapeutic uses are distinct from later clinical development. It does not establish universal safety or effectiveness. Ridley, Craddock and la Touche are acknowledged separately from Fleming’s byline. WRS read publicly visible transcribed source sections; an institutional PDF, figures and full table audit remain unacquired.",
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        "description": "The discovery report and its proposed therapeutic uses are distinct from later clinical development. It does not establish universal safety or effectiveness. Ridley, Craddock and la Touche are acknowledged separately from Fleming’s byline. WRS read publicly visible transcribed source sections; an institutional PDF, figures and full table audit remain unacquired.",
        "domain": "Microbiology"
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      "sources": [
        {
          "citation": "Fleming, On the Antibacterial Action of Cultures of a Penicillium, with Special Reference to their Use in the Isolation of B. influenzæ, British Journal of Experimental Pathology 10, 226–236 (1929)",
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      "statement": "# Fleming: antibacterial activity of Penicillium cultures\n\nReported a mould-associated antibacterial effect, named the active culture filtrate penicillin, and used differences in bacterial susceptibility to aid isolation of influenza bacilli.\n\n## Scientific scope\n\nThe discovery report and its proposed therapeutic uses are distinct from later clinical development. It does not establish universal safety or effectiveness. Ridley, Craddock and la Touche are acknowledged separately from Fleming’s byline. WRS read publicly visible transcribed source sections; an institutional PDF, figures and full table audit remain unacquired.\n\n## Reading status\n\nThis is a source-linked WRS catalogue note. A full explanatory guide and independent scientific reconstruction have not been completed for this entry. Read the identified original work for its complete narrative and arguments.\n\n## People and systems\n\nAlexander Fleming\n\nListed source contributors; individual labor shares are not measured\n\n\n\n## Original sources\n\n- [Fleming, On the Antibacterial Action of Cultures of a Penicillium, with Special Reference to their Use in the Isolation of B. influenzæ, British Journal of Experimental Pathology 10, 226–236 (1929)](https://www.scribd.com/document/353815574/brjexppathol00255-0037-pdf)\n- [NLM/PMC bibliographic record for Fleming’s 1929 paper](https://pmc.ncbi.nlm.nih.gov/articles/PMC2048009/?page=1)\n",
      "summary": "Reported a mould-associated antibacterial effect, named the active culture filtrate penicillin, and used differences in bacterial susceptibility to aid isolation of influenza bacilli.",
      "title": "Fleming: antibacterial activity of Penicillium cultures"
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    "title": "Fleming: antibacterial activity of Penicillium cultures",
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    "what_changed": "Reported a mould-associated antibacterial effect, named the active culture filtrate penicillin, and used differences in bacterial susceptibility to aid isolation of influenza bacilli.",
    "scope": "Reported a mould-associated antibacterial effect, named the active culture filtrate penicillin, and used differences in bacterial susceptibility to aid isolation of influenza bacilli. Scope limitation: The discovery report and its proposed therapeutic uses are distinct from later clinical development. It does not establish universal safety or effectiveness. Ridley, Craddock and la Touche are acknowledged separately from Fleming’s byline. WRS read publicly visible transcribed source sections; an institutional PDF, figures and full table audit remain unacquired.",
    "evidence_summary": "Assessment uses the catalogue-linked source evidence for the stated contribution. The discovery report and its proposed therapeutic uses are distinct from later clinical development. It does not establish universal safety or effectiveness. Ridley, Craddock and la Touche are acknowledged separately from Fleming’s byline. WRS read publicly visible transcribed source sections; an institutional PDF, figures and full table audit remain unacquired.",
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      {
        "title": "Fleming, On the Antibacterial Action of Cultures of a Penicillium, with Special Reference to their Use in the Isolation of B. influenzæ, British Journal of Experimental Pathology 10, 226–236 (1929)",
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