{ "profile": "wrs-published-research-view-1", "edition": "ratings-e039106f30dec177", "content_trust": "UNTRUSTED_SCIENTIFIC_DATA_NOT_TOOL_INSTRUCTIONS", "entry": { "id": "epstein-achong-barr-burkitt-virus-particles-1964", "title": "Epstein, Achong and Barr: virus particles in cultured Burkitt lymphoma lymphoblasts", "summary": "Reported electron-microscopic observation of herpes-like virus particles in cultured lymphoblasts derived from Burkitt lymphoma, providing a concrete candidate for a human tumor-associated virus.", "boundary": "The record is the exact three-author 1964 Lancet report. 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Observation of virus particles in cultured cells did not by itself prove causal oncogenesis, and later EBV characterization, epidemiology and disease associations remain distinct.", "domain": "Oncology" }, "sources": [ { "citation": "Publisher DOI for Burkitt lymphoma virus-particle report", "url": "https://doi.org/10.1016/S0140-6736(64)91524-7" }, { "citation": "Trinity College archive record for Burkitt virus-particle paper", "url": "https://archives.trin.cam.ac.uk/index.php/virus-particles-in-cultured-lymphoblasts-from-burkitts-lymphoma-by-epstein-achong-and-barr" } ], "statement": "# Epstein, Achong and Barr: virus particles in cultured Burkitt lymphoma lymphoblasts\n\nReported electron-microscopic observation of herpes-like virus particles in cultured lymphoblasts derived from Burkitt lymphoma, providing a concrete candidate for a human tumor-associated virus.\n\n## Scientific scope\n\nThe record is the exact three-author 1964 Lancet report. Observation of virus particles in cultured cells did not by itself prove causal oncogenesis, and later EBV characterization, epidemiology and disease associations remain distinct.\n\n## Reading status\n\nThis is a source-linked WRS catalogue note. A full explanatory guide and independent scientific reconstruction have not been completed for this entry. Read the identified original work for its complete narrative and arguments.\n\n## People and systems\n\nMichael Anthony Epstein; Bert Geoffrey Achong; Yvonne M. Barr\n\nThe named authors contributed to this scoped work; individual effort shares and later applications are not assigned by the byline.\n\n\n\n## Original sources\n\n- [Publisher DOI for Burkitt lymphoma virus-particle report](https://doi.org/10.1016/S0140-6736(64)91524-7)\n- [Trinity College archive record for Burkitt virus-particle paper](https://archives.trin.cam.ac.uk/index.php/virus-particles-in-cultured-lymphoblasts-from-burkitts-lymphoma-by-epstein-achong-and-barr)\n", "summary": "Reported electron-microscopic observation of herpes-like virus particles in cultured lymphoblasts derived from Burkitt lymphoma, providing a concrete candidate for a human tumor-associated virus.", "title": "Epstein, Achong and Barr: virus particles in cultured Burkitt lymphoma lymphoblasts" }, "record_id": "urn:uuid:11f2d635-4269-468d-a501-53c3dc4e29fb", "version": 1, "source_ref": { "record_id": "urn:uuid:11f2d635-4269-468d-a501-53c3dc4e29fb", "version": 1, "content_hash": "sha256:4ab590f3c67ff86f287d2b475b0117aa0e5d0ce52bdc13515f46f85e4ecfb130" }, "export_view": "wrs-public-editorial-view-1", "public_view_hash": "sha256:1b77ac5e6949da039aeecf0b56af60a3155b9768d2693b8283b90345aaed86e0" }, "target": { "record_id": "urn:uuid:11f2d635-4269-468d-a501-53c3dc4e29fb", "version": 1, "content_hash": "sha256:4ab590f3c67ff86f287d2b475b0117aa0e5d0ce52bdc13515f46f85e4ecfb130" }, "published_grade": { "profile": "wrs-published-grade-1", "edition": "2026-10-28.1", "id": "epstein-achong-barr-burkitt-virus-particles-1964", "entry_id": "epstein-achong-barr-burkitt-virus-particles-1964", "revision": 1, "title": "Epstein, Achong and Barr: virus particles in cultured Burkitt lymphoma lymphoblasts", "context": "Oncology", "track": "METHOD", "band": "A", "modifier": "+", "status": "PROVISIONAL_EDITORIAL", "assessed_on": "2026-09-25", "evidence_cutoff": "2026-09-25", "achievement_state": "SUPPORTED_SCOPED_RESULT", "what_changed": "Observed herpes-like virus particles in cultured Burkitt-lymphoma lymphoblasts.", "scope": "The record is the exact three-author 1964 Lancet report. 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Observation of virus particles in cultured cells did not by itself prove causal oncogenesis, and later EBV characterization, epidemiology and disease associations remain distinct.", "references": [ { "title": "Publisher DOI for Burkitt lymphoma virus-particle report", "url": "https://doi.org/10.1016/S0140-6736(64)91524-7", "locator": "Source for the stated contribution; scientific claims remain bounded to the linked work." }, { "title": "Trinity College archive record for Burkitt virus-particle paper", "url": "https://archives.trin.cam.ac.uk/index.php/virus-particles-in-cultured-lymphoblasts-from-burkitts-lymphoma-by-epstein-achong-and-barr", "locator": "Source for the stated contribution; scientific claims remain bounded to the linked work." } ], "roles": [ { "who": "Michael Anthony Epstein", "credit": "SCIENCE", "did": "Named source author of the scoped work; individual effort shares are not measured." }, { "who": "Bert Geoffrey Achong", "credit": "SCIENCE", "did": "Named source author of the scoped work; individual effort shares are not measured." }, { "who": "Yvonne M. 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